The Hitchhiker’s Guide to the Galaxy, by Douglas Adams: Arthur Dent, a refugee from the late planet Earth and his pal from the planet Betelgeuse, Ford Prefect, thumb their way thru comic misadventures throughout the Universe.
The Lunar Chronicles Series, by Marissa Meyer: As plague ravages the overcrowded Earth, observed by a ruthless lunar people, Cinder, a gifted mechanic and cyborg, becomes involved with handsome Prince Kai and must uncover secrets about her past in order to protect the world in this futuristic take on the Cinderella story.
The Eye of Minds, by James Dashner: Michael is a skilled internet gamer in a world of advanced technology. When a cyber-terrorist begins to threaten players, Michael is called upon to seek him and his secret's out
Fahrenheit 451, by Ray Bradbury: In a future totalitarian state where books are banned and destroyed by the government, Guy Montag, a fireman in charge of burning books, meets a revolutionary schoolteacher who dares to read and a girl who tells him of a past when people did not live in fear.
Enders Game, by Orson Scott Card: Child-hero Ender Wiggin, must fight a desperate battle against a deadly alien race if mankind is to survive
Ready Player One, by Ernest Cline: This is a spectacularly genre-busting, ambitious, and charming debut-- part quest novel, part love story, and part virtual space opera set in a universe where spell-slinging mages battle giant Japanese robots, entire planets are inspired by Blade Runner, and flying DeLoreans achieve light speed.
After the Snow, by S.D. Crockett: Fifteen-year-old Willo Blake, born after the 2059 snows that ushered in a new ice age, encounters outlaws, halfmen, and an abandoned girl as he journeys in search of his family, who mysteriously disappeared from the freezing mountain that was their home.
Dangerous, by Shannon Hale: When aspiring astronaut Maisie Danger Brown, who was born without a right hand, and the other space camp students get the opportunity to do something amazing in space, Maisie must prove how dangerous she can be and how far she is willing to go to protect everything she has ever loved.
The Adoration of Jenna Fox, by Mary E. Pearson: In the not-too-distant future, when biotechnological advances have made synthetic bodies and brains possible but illegal, a seventeen-year-old girl, recovering from a serious accident and suffering from memory lapses, learns a startling secret about her existence.
These Broken Stars, by Amie Kaufman & Meagan Spooner: Two star-crossed lovers must fight for survival when they crash land on a seemingly uninhabited planet.
Insignia, by S. J. Kinkaid: Tom, a fourteen-year-old genius at virtual reality games, is recruited by the United States Military to begin training at the Pentagon Spire as a Combatant in World War III, controlling the mechanized drones that do the actual fighting off-planet.
Across the Universe, by Beth Revis: Teenaged Amy, a cryogenically frozen passenger on the spaceship Godspeed, wakes up to discover that someone may have tried to murder her.
Uglies, by Scott Westerfeld: Just before their sixteenth birthdays, when they will be transformed into beauties whose only job is to have a great time, Tally's best friend runs away and Tally must find her and turn her in, or never become pretty at all.